Published November 28, 2018 | Version v1
Dataset Open

Size-exclusion chromatography (SEC) - multi-angle light scattering (MALS) analysis of HTT and HTT-HAP40 complex samples – 2018/11/27

Authors/Creators

  • 1. Structural Genomics Consortium, University of Toronto

Description

Project - Huntingtin structure-function open lab notebook. 

Experiment - Size-exclusion chromatography (SEC) - multi-angle light scattering (MALS) analysis of HTT and HTT-HAP40 complex samples – 2018/11/27. To investigate how monodispersity of HTT and HTT-HAP40 samples. 

Notes

Dr. Harding is the recipient of the Huntington's Disease Society of America Berman Topper Career Development Fellowship which funds and supports this research. The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome. Thanks to OICR for access to their MALS equipment and Ahmed Aman for his assistance in running experiments.

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