Journal article Open Access

Caenorhabditis monodelphis sp. n.: defining the stem morphology and genomics of the genus Caenorhabditis

Dieter Slos; Walter Sudhaus; Lewis Stevens; Wim Bert; Mark Blaxter

Background

The genus Caenorhabditis has been central to our understanding of metazoan biology. The best-known species, Caenorhabditis elegans, is but one member of a genus with around 50 known species, and knowledge of these species will place the singular example of C. elegans in a rich phylogenetic context. How did the model come to be as it is today, and what are the dynamics of change in the genus?

Results

As part of this effort to "put C. elegans in its place", we here describe the morphology and genome of Caenorhabditis monodelphis sp. n., previously known as Caenorhabditis sp. 1. Like many other Caenorhabditis, C. monodelphis sp. n. has a phoretic association with a transport host, in this case with the fungivorous beetle Cis castaneus. Using genomic data, we place C. monodelphis sp. n. as sister to all other Caenorhabditis for which genome data are available. Using this genome phylogeny, we reconstruct the stemspecies morphological pattern of Caenorhabditis.

Conclusions

With the morphological and genomic description of C. monodelphis sp. n., another key species for evolutionary and developmental studies within Caenorhabditis becomes available. The most important characters are its early diverging position, unique morphology for the genus and its similarities with the hypothetical ancestor of Caenorhabditis.

Files (167.3 MB)
Name Size
assembly_stats_abv500.txt md5:3fc85dd47ebd8f596fa1356efa9be1f6 512 Bytes Download
Caenorhabditis_phylogeny_supermatrix.nex md5:cab16d5476229f2c407cbf0df795195b 2.6 MB Download
CSP1.caenorhabditis_sp1.BLAXTERLAB.annotation.gff3 md5:2f03c7a08bb09a25246bbf7a11f584d7 41.1 MB Download
CSP1.caenorhabditis_sp1.BLAXTERLAB.genome.abv500.fa md5:e6848bfd4645e6fa556d9adf0b89e5b3 115.2 MB Download
CSP1.caenorhabditis_sp1.BLAXTERLAB.protein.fa md5:b5c92f0c7da7be292e8d7d8631c161ae 8.2 MB Download
ONE-TO-ONES_Orthologous_Groups.txt md5:1d4dfa73b1b1a8dda6353b6570f9cbbc 139.0 kB Download

Share

Cite as