EFFICACY OF STREOIDS IN NEONATES WITH MECONIUM ASPIRATION

Objectives: The objective of study the was to know about effectiveness of corticosteroid therapy in neonates with meconium aspiration syndrome in comparison with control.

Materials and Methods:

The study was conducted in pediatrics unit Punjab medical college Allied/ DHQ hospital Faisalabad in the duration of six months after the approval of synopsis.

Results: Out of 92 cases (46 in each group) 46.67% (n=19) in A-Group and 56.67% (n=22) in other B-Group were between 1-3 hours of life, 36.67%  which is (n=16) in A-Group and 30% which is (n=14) in B-Group were between 4-6 hours while only 16.67% which is  (n=11) in A-Group and 13.33% which is (n=10) in B-Group were between 6-8 hours of life, mean and sd was calculated as 3.78+2.26 in A-Group and 4.12+2.77 years in B-Group, 63.33%  (n=29) in A-Group and 56.67% (n=26) in B-Group were male while 36.67% (n=17) in A-Group and 43.33% (n=20) in B-Group were females, mean duration of stay in hospital was significantly reduced in children administered corticosteroid therapy.

Conclusion: Treatment with corticosteroid in neonates suffering from meconium aspiration syndrome is effective in terms of hospital stay duration while comparing with symptomatic treatment only.

Key Words:  Meconium aspiration syndrome, neonates, corticosteroid therapy, Symptomatic