Published January 1, 2023
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Table 1 in A mini-review: Potential of Phyllanthus niruri L as immunostimulators in fish aquaculture
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- 1. Department of Fisheries, Faculty of Fishery and Marine Science, Universitas Padjadjaran, Bandung, Indonesia
Description
Table 1: Applications of Phyllanthus niruri L. Sebagai Immunostimulant
| Jenis Ikan | Treatment | Metode Uji Tantang | Hasil | Ref |
|---|---|---|---|---|
| Oreochromis mossambicus | Administration of P. niruri aqueous extract via intraperitoneal. | Injection Fish were injected intraperitoneally with Sheep red blood cells (SRBC). The first dose of 0.1 mL of 5% and the second dose (booster) of 0.1 mL of 25% | P. niruri extract dose of 20 mg/fish body weight resulted in a maximum increase in antibody levels on day 15. | [34] |
| Oreochromis mossambicus | Administration of P. niruri leaf aqueous extract by intraperitoneal injection. | Fish were injected intraperitoneally with HA-BSA (heat aggregated-bovine serum albumin) with a concentration of 5 mg as much as 100 μL. | A dose of P. niruri extract of 0.02 mg/kg body weight resulted in a maximum increase in neutrophil levels on the 6th day. | [34] |
| Oreochromis niloticus | Administration of P. niruri leaf aqueous extract by injection. | Infecting fish by injection with Aeromonas hydrophila bacteria. | The concentration of 50 mg significantly resulted in the highest survival, which was 76.7%. | [35] |
| Cyprinus carpio | Giving water extract of P. niruri leaves through feed. | Infection of fish with A. hydrophila 103 CFU in cohabitation through water media in rearing aquariums. | The concentration of 2% (10 g/500 g of feed) resulted in the highest fish survival, namely 100%. | [36] |
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References
- 34. Muthulakshmi M, Subramani PA, Michael RD. Immunostimulatory effect of the aqueous leaf extract of Phyllanthus niruri on the specific and nonspecific immune responses of Oreochromis mossambicus Peters. Iranian Journal of Veterinary Research. 2016; 17 (3): 200 - 202.
- 35. Wulandari R. Effectiveness of Meniran (Phyllanthus niruri) Leaf Extract by injection for the prevention of bacterial infection (Aeromonas hydrophila) in Tilapia (Oreochromis niloticus). Bachelor Thesis, Universitas Muhammadiyah Purwokerto; c 2014.
- 36. Sunitha C, Mettilda S, Vinoliya J. Effect of dietary intake of Phyllanthus niruri L. on fingerlings of freshwater fish, Cyprinus carpio L. International Journal of Fisheries and Aquatic Studies. 2017; 5 (1): 352 - 359.