Published July 31, 2021 | Version v1

Table 5 in The potential of Apiaceae species as sources of singular phytochemicals and plant-based pesticides

  • 1. * & Biology Department, Faculty of Science, University of Porto, Rua Do Campo Alegre S / n, 4169 - 007, Porto, Portugal & * & GreenUPorto - Sustainable Agrifood Production, Research Centre, Department of Biology, Faculty of Science, University of Porto, Rua Do Campo Alegre S / n, 4169 - 007, & * & CITAB, Centre for the Research and Technology of Agro-Environmental and Biological Sciences, Universidade de Tr´as-os-Montes e Alto Douro, 5000 - 801, Vila Real,

Description

Table 5 General cytotoxicity induced by different classes of phytochemicals and reported events taking place at the cellular level. a

EOsDamage the cellular membrane and organelles Mitochondrial dysfunction-induced reactive oxygen species accumulation Decreased ATPase and dehydrogenase activities Causes nuclear and cytoplasmic mutagenicity
Most monoterpenesCause reduction in the number of intact mitochondria and Golgi bodies Impair respiration and photosynthesis
HydrocarbonsAct as solvents of the cellular membrane compromising its integrity and increasing the movement of other molecules across the cell
PhenolicsProduce very reactive phenoxyl radicals when oxidized by contact with reactive oxygen species
Phenols, aldehydes, and alcoholsAct as prooxidants on proteins and DNA
FurocoumarinsAct as photoactive molecules; Produce radical reactions and oxygen singlet; Crosslink both strands of DNA by binding to pyrimidine bases, thereby inhibiting DNA replication and transcription.

a Sources: Bakkali et al. (2008); Tripathi et al. (2009).

Notes

Published as part of Sousa, Rose Marie O. F., Cunha, Ana C. & Fernandes-Ferreira, Manuel, 2021, The potential of Apiaceae species as sources of singular phytochemicals and plant-based pesticides, pp. 21 in Phytochemistry (112714) 187 on page 21, DOI: 10.1016/j.phytochem.2021.112714, http://zenodo.org/record/8259087

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Journal article: 10.1016/j.phytochem.2021.112714 (DOI)
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References

  • Bakkali, F., Averbeck, S., Averbeck, D., Idaomar, M., 2008. Biological effects of essential oils - a review. Food Chem. Toxicol. 46 (2), 446 - 475. https: // doi. org / 10.1016 / j. fct. 2007.09.106.