Published July 31, 2021
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Table 5 in The potential of Apiaceae species as sources of singular phytochemicals and plant-based pesticides
Authors/Creators
- 1. * & Biology Department, Faculty of Science, University of Porto, Rua Do Campo Alegre S / n, 4169 - 007, Porto, Portugal & * & GreenUPorto - Sustainable Agrifood Production, Research Centre, Department of Biology, Faculty of Science, University of Porto, Rua Do Campo Alegre S / n, 4169 - 007, & * & CITAB, Centre for the Research and Technology of Agro-Environmental and Biological Sciences, Universidade de Tr´as-os-Montes e Alto Douro, 5000 - 801, Vila Real,
Description
Table 5 General cytotoxicity induced by different classes of phytochemicals and reported events taking place at the cellular level. a
| EOs | Damage the cellular membrane and organelles Mitochondrial dysfunction-induced reactive oxygen species accumulation Decreased ATPase and dehydrogenase activities Causes nuclear and cytoplasmic mutagenicity |
|---|---|
| Most monoterpenes | Cause reduction in the number of intact mitochondria and Golgi bodies Impair respiration and photosynthesis |
| Hydrocarbons | Act as solvents of the cellular membrane compromising its integrity and increasing the movement of other molecules across the cell |
| Phenolics | Produce very reactive phenoxyl radicals when oxidized by contact with reactive oxygen species |
| Phenols, aldehydes, and alcohols | Act as prooxidants on proteins and DNA |
| Furocoumarins | Act as photoactive molecules; Produce radical reactions and oxygen singlet; Crosslink both strands of DNA by binding to pyrimidine bases, thereby inhibiting DNA replication and transcription. |
a Sources: Bakkali et al. (2008); Tripathi et al. (2009).
Notes
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- Is part of
- Journal article: 10.1016/j.phytochem.2021.112714 (DOI)
- Journal article: urn:lsid:plazi.org:pub:3A2E1A6BFFA0F4522B4F6C7A385EFFEA (LSID)
- Journal article: http://publication.plazi.org/id/3A2E1A6BFFA0F4522B4F6C7A385EFFEA (URL)
- Journal article: http://zenodo.org/record/8259087 (URL)
References
- Bakkali, F., Averbeck, S., Averbeck, D., Idaomar, M., 2008. Biological effects of essential oils - a review. Food Chem. Toxicol. 46 (2), 446 - 475. https: // doi. org / 10.1016 / j. fct. 2007.09.106.