Published March 12, 2025 | Version v1
Dataset Open

2 - Raw movies for 'Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes'

Authors/Creators

  • 1. ROR icon École Polytechnique Fédérale de Lausanne

Description

Single-molecule TIRF dataset (2/6) for the 'Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes'.

Binding of PRC1.1 and PRC1.4 on H2Aub containing chromatin fibers. Ubiquitylation control in the absence of E3 on wild type H2A (H2A-wt) and H2AK118R/K119R (H2A-RR) containing chromatin fibers with E2~Ub.

Files

Files (49.2 GB)

Name Size
md5:7a7cc3908a776ac731cbab1c3cb8aa0b
12.5 GB Download
md5:5a6aaf5cde57817c1b28069c86548ce6
20.3 GB Download
md5:dba20a7bfce0616b94ad95c3c4d1d828
16.4 GB Download

Additional details

Related works

Is supplement to
Workflow: 10.5281/zenodo.14810849 (DOI)

Funding

European Commission
chromo-SUMMIT - Decoding dynamic chromatin signaling by single-molecule multiplex detection 724022
Swiss National Science Foundation
Dynamic mechanisms of DNA binding factors to invade and reshape chromatin structure 200604