Pharmacoepigenomic impact of Anti-hypertensive drugs on DNA methylation: A genomewide methylation study
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Description
Supplementary Materials: The following supporting information can be downloaded at: www.mdpi.com/xxx/s1,
Figure S1: Methodology.
Figure S2: Up and Down bar plot representing the DMPs that are being discussed in the paper.
Table S1: List of primer and the primer sequence of epigenetic genes in the mRNA expression analysis.
Table S2: Effect of antihypertensive drugs at varying concentration and duration on the mRNA expression of DNA methyltransferases and DNA demethylases.
Table S3: List of common probes and genes that are differentially methylated after AMLO (6-hours and 24-hours) treatment and after ENALA (6-hours and 24-hours) treatment.
Table S4: List of probes and genes that were reverted upon duration after treatment.
Table S5: List of Gene ontology terms, Fold enrichment, FDR value, Count and Class of each treatment.