Raw Flow cytometry data files for Fig 3 and S3 Fig of the publication "Interferon Regulatory Factor 4 mediates nonenzymatic IRE1 dependency in multiple myeloma cells"

These FCS files are part of the supplementary data for Figures 3B and S3J of the following publication:

Interferon Regulatory Factor 4 mediates nonenzymatic IRE1 dependency in multiple myeloma cells

(3B) Effect of IRF4, IRE1 or XBP1 silencing on number of cell divisions. AMO1 shIRE1 Cl.1, shIRF4 Cl.1 or shXBP1 Cl.1 cells were stained with CFSE-type dye and incubated in the absence (filled shapes) or presence (open shapes) of Dox (0.2 μg/mL) and analyzed by flow cytometry. Etoposide (Eto, 25 μM, dashed line) was used as a non-proliferative control. Representative experiment out of 3 independent replicates.

(S3J) Effect of IRE1 and IRF4 silencing on cell divisions in KMS27 cells. KMS27 shIRE1, shIRF4 or shNTC were stained with CFSE-type dye and incubated in the absence (filled shapes) or presence (open shapes) of Dox (0.2 μg/mL) and analyzed by flow cytometry. Etoposide (Eto, 25 μM, dashed line) was used as a non-proliferative control.