Published November 5, 2018 | Version v2

The genetic basis of mutation rate variation in yeast [data and script]

  • 1. University of California, Los Angeles

Description

This dataset contains the data and the scripts for the study of exploring the genetic basis of mutation rate in yeast (https://www.biorxiv.org/content/early/2018/06/04/338723). 

  • The genotype folder contains the genotype for 1040 segreants, as well as the genotype for the 843 segregants used for QTL mapping.
  • The mutation_spectrum contains the codes for MiSeq data processing, mutation variants calling, mutation spectrum detection and plotting.  
  • The phenotype folder contains the mutations per culture (parameter m) for 843 segreants, as well as the number of cells per culture (parameter N) for the corresponding segregants.
  • The qtl_mapping folder contains the codes for QTL mapping and the codes to plot the correlation between mutation rate and mutagen resistance.

Files

Mutation-rate.zip

Files (10.8 MB)

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