Published February 14, 2025 | Version v1
Dataset Restricted

Spatial profiling of human pancreas during type 1 diabetes progression

Authors/Creators

  • 1. ROR icon Helmholtz Zentrum München
  • 2. ROR icon University of California, San Diego

Contributors

Project leader:

  • 1. ROR icon University of California, San Diego
  • 2. ROR icon Helmholtz Zentrum München

Description

Spatial transcriptomic profiling on the CosMx platform (NanoString, Seattle, WA). Pancreatic tissue from six nPOD organ donors - three with T1D (6228, 6247, 6456) and three without diabetes (6431, 6339, 6229), matched by age and sex. For each donor, five consecutive FFPE tissue sections from the pancreatic body region were cut at a thickness of 4 microns.

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