BIOACTIVITY OF GREEN SYNTHESIZED SILVER NANOPARTICLES FROM CALOTROPIS GIGANTEA (L.) R.BR LEAVES AND STEMS

In this study, we have synthesised and analysed the potential efficiency of the green synthesized silver nanoparticles (AgNPs) using Calotropis gigantea (Linn) R. Br leaves and stems extract as a reducing and stabilizing agent under surfactant-free conditions. The formation of AgNPs is monitored by recording the UV–vis absorption spectra. The green synthesized AgNPs were characterized by UV–visible, FT-IR, XRD, EDAX, and SEM techniques. The green synthesized AgNPs of C. gigantea (Linn) R. Br leaves and stems were significantly showed more effective free radical scavenging activity. Synthesised silver nanoparticles shows potent antibacterial, antifungal, antibiofilm, antiangiogenic, mosquitocidal activity. Also the green synthesized silver nanoparticles exhibit cytotoxicity against Hep2 and AGS cell lines, further it may use effectively in treatment of carcinomas. The results observed in the present study showed the promising potential of C. gigantea (Linn.) R.Br- synthesised AgNPs for the development of novel antimicrobials, antibiofilm, and antiangiogenesis, mosquitocidal, anticancer and for various purposes.

Keywords: Green synthesizes AgNPs, UV–visible, FT-IR, XRD, EDX, and SEM.