Published February 6, 2025
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Innovative Physics-Engineered Approach to Leukemia Treatment
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Description
This research proposes a novel extracorporeal leukemia filtration device integrating ultrasonic acoustic separation and immuno-magnetic targeting. The method enables rapid reduction of leukemic burden, minimizing chemotherapy toxicity and accelerating patient stabilization. It presents a physics-engineered approach applicable to acute leukemia management.
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Dates
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2025-02-06
References
- Antfolk, M., & Laurell, T. (2017). Continuous flow microfluidic separation based on ultrasound. Nature Methods, 14(3), 279-282. https://doi.org/10.1038/nmeth.4307
- Bertaina, A., et al. (2017). Advancements in leukapheresis technology: Challenges and opportunities. Blood, 130(11), 123-134. https://doi.org/10.1182/blood-2017-02-764332
- DeAngelo, D. J., et al. (2015). Advances in ALL therapy: A clinical perspective. Journal of Clinical Oncology, 33(27), 3105-3112. https://doi.org/10.1200/JCO.2015.61.0983
- Kemper, C., et al. (2021). Magnetically targeted immunotherapy in leukemia models. Stem Cell Research & Therapy, 12(1), 210. https://doi.org/10.1186/s13287-021-02273-2
- Kantarjian, H., et al. (2020). Current treatment strategies for acute leukemia. The New England Journal of Medicine, 382(11), 1084-1096. https://doi.org/10.1056/NEJMra1905639