Published January 28, 2025 | Version v1
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IMPROVE Anti-inflammatory effects of sulphadoxine-pyrimethamine for intermittent preventive treatment for malaria in pregnancy (GHDC-SI-ID-45)

Authors/Creators

  • 1. ROR icon Liverpool School of Tropical Medicine

Contributors

  • 1. ROR icon Liverpool School of Tropical Medicine

Description

The Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa (IMPROVE) study is a 3-arm malaria chemoprevention trial with monthly intermittent preventive treatment in pregnancy, or IPTp, in Malawi, Kenya and Tanzania (Clinicaltrials.gov: NCT03208179Trial). Using Olink, we profiled plasma cytokine levels in pregnant women at enrolment, around 28 weeks and 36 weeks (or delivery) at Stanford's Human Immune Monitorin Center (HIMC).

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Additional details

Funding

Bill & Melinda Gates Foundation
Center for Human Systems Immunology INV-008378