Published December 13, 2024
| Version v1
Dataset
Open
EndoMAP.v1 charts the structural landscape of human early endosome complexes_AlphaFold-Multimer
Authors/Creators
-
1.
Vrije Universiteit Amsterdam
-
2.
Harvard Medical School
Contributors
Project leader (2):
- 1. Howard Hughes Medical Institute - Harvard Medical School
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2.
Harvard Medical School
Description
This deposit contains alphafold predictions (.pdb and .json files) for alphafold multimer predictions of protein pairs and 3-way cliques identified by cross linking proteomics with DSSO crosslinker in the context of purified EEA1-positive endosomes. Predictions were made with alphafold multimer (ColabFold v 1.5.2 )[Mirdita, M. et al. ColabFold: making protein folding accessible to all. Nat Methods 19, 679-682 (2022). https://doi.org:10.1038/s41592-022-01488-1].
Reference:
Gonzalez-Lozano, M.A., Schmid, E.W., Miguel Whelan, E. et al. EndoMAP.v1 charts the structural landscape of human early endosome complexes. Nature 643, 252–261 (2025). https://doi.org/10.1038/s41586-025-09059-y
Files
AFM_EndoMAP_SPOC_analysis.csv
Files
(23.9 GB)
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md5:d7a9adea15c0ebfefc8a02e0f5434312
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7.0 MB | Preview Download |
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md5:f2ada2310b5718894a01edd50867cb6c
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20.4 GB | Preview Download |
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md5:2f918509fdfe883c71486ccb02798c0f
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85.8 kB | Preview Download |
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md5:95036a630722676e0dcd7a099d40442c
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3.5 GB | Preview Download |
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md5:7e81736d48081841cb3918401281d9e1
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3.1 kB | Preview Download |
Additional details
Funding
- Aligning Science Across Parkinson's
- Mechanisms Overwhelming Protein and Organelle Quality Control in Parkinson’s Disease 000282