Published September 21, 2018
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Developing a Tryptophan Fluorescence Assay for Screening Ligands against USP5 Zf-UBD
- 1. University of Toronto, Structural Genomics Consortium
Description
Development of a fluorescence based assay by measuring changes in UV tryptophan fluorescence of USP5 zinc finger ubiquitin binding domain (Zf-UBD) with addition of ligands
Notes
Funding Acknowledgment: The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.
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20180921_Trpfluorescence_zenodo.pdf
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