Published November 26, 2024
| Version v1
Dataset
Open
Immunophenotyping of peripheral blood mononuclear cells after out-of-hospital cardiac arrest: Flow cytometry of human peripheral blood mononuclear cells
Description
Samples 1–12: Healthy subjects, NK cells
Samples 13–23: Post-cardiac arrest, Early, Good outcomes, NK cells
Samples 24–36: Post-cardiac arrest, Early, Poor outcomes, NK cells
Samples 37–44: Post-cardiac arrest, Late, Good outcomes, NK cells
Samples 45–51: Post-cardiac arrest, Late, Poor outcomes, NK cells
Samples 52–61: Healthy subjects, Monocytes
Samples 62–71: Post-cardiac arrest, Early, Good outcomes, Monocytes
Samples 72–81: Post-cardiac arrest, Early, Poor outcomes, Monocytes
Samples 82–87: Post-cardiac arrest, Late, Good outcomes, Monocytes
Samples 88–93: Post-cardiac arrest, Late, Poor outcomes, Monocytes
Samples 1–51 are related to Figures 3D, 4C, S3, S4G
Samples 52–93 are related to Figures 4B, S2, S4F
Matching samples analyzed in the single-cell RNA-seq:
Single-cell RNA-seq samples GEO accession #: GSE200118
Bulk RNA-seq samples GEO accession #: GSE200117
| Sample ID | Single-cell RNA-seq | Bulk Tim3+ NK cell | Bulk Tim3- NK cell | Bulk Nectin2+ monocyte | Bulk Nectin2- monocyte |
| 2_Healthy_NK cell_2 | GSM6011697 | GSM6011454 | GSM6011474 | ||
| 53_Healthy_Monocyte_2 | GSM6011697 | GSM6011614 | GSM6011626 | ||
| 16_CA_Early_Good_NK cell_4 | GSM6011703 | ||||
| 64_CA_Early_Good_Monocyte_3 | GSM6011703 | GSM6011504 | GSM6011560 | ||
| 19_CA_Early_Good_NK cell_7 | GSM6011706 | ||||
| 67_CA_Early_Good_Monocyte_6 | GSM6011706 | GSM6011508 | GSM6011563 | ||
| 17_CA_Early_Good_NK cell_5 | GSM6011713 | ||||
| 65_CA_Early_Good_Monocyte_4 | GSM6011713 | GSM6011506 | GSM6011561 | ||
| 24_CA_Early_Poor_NK cell_1 | GSM6011714 | GSM6011377 | GSM6011432 | ||
| 29_CA_Early_Poor_NK cell_6 | GSM6011721 | GSM6011394 | GSM6011430 | ||
| 74_CA_Early_Poor_Monocyte_3 | GSM6011721 | GSM6011516 | GSM6011553 | ||
| 38_CA_Late_Good_NK cell_2 | GSM6011709 | ||||
| 83_CA_Late_Good_Monocyte_2 | GSM6011709 | GSM6011511 | GSM6011597 | ||
| 46_CA_Late_Poor_NK cell_2 | GSM6011718 | GSM6011415 | GSM6011450 | ||
| 45_CA_Late_Poor_NK cell_1 | GSM6011719 | GSM6011408 | GSM6011444 | ||
| 88_CA_Late_Poor_Monocyte_1 | GSM6011719 | GSM6011538 | GSM6011575 |
Files
Files
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Additional details
Funding
- American Heart Association
- Transformational Project Award: I-CAN: A collaborative research network to discover immunological therapies for cardiac arrest 20TPA35500016
- American Heart Association
- NKT cells protect against brain injury after cardiac arrest and resuscitation 15FTF25080205
- National Institutes of Health
- Resolution of inflammation after cardiac arrest R01HL16687
Dates
- Collected
-
2014-01-01/2020-03-31