Published May 31, 2018
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Table 4 in Phytoconstituents from Vernonia glaberrima Welw. Ex O. Hoffm. leaves and their cytotoxic activities on a panel of human cancer cell lines
Authors/Creators
- 1. Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, 25200 Kuantan, Pahang DM, Malaysia
- 2. School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bandar Baru Bangi, Selangor DE, Malaysia
- 3. Atta-ur-Rahman Institute for Natural Products Discovery (AuRIns), Universiti Teknologi MARA, Bandar Puncak Alam, Selangor DE, Malaysia & Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor DE, Malaysia
- 4. Department of Biomedical Science, Kulliyah of Allied Health Sciences, International Islamic University Malaysia, 25200 Kuantan, Pahang DM, Malaysia
- 5. Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University, Sokoto P. M. B 2346, Sokoto State, Nigeria
Description
Table 4 Docking scores of 5-methylcoumarin-4-β- glucoside and 4-hydroxy-5-methylcoumarin on carbonic anhydrase IX (CAIX) (PDB ID 3IAI).
| Name | Free binding energy (kcal/mol) | Estimated inhibition constant (Ki) | |
|---|---|---|---|
| 1 | 5-Methylcoumarin-4-β- glucoside | − 6.97 | 7.78 μM |
| 2 | 4-Hydroxy-5-methylcoumarin | − 5.70 | 66.17 μM |
| 3 | Co-crystallized ligand | − 6.01 | 39.32 μM |
Notes
Published as part of Alhassan, A. M., Ahmed, Q. U., Latip, J., Shah, S. A. A., Khan, A. ' a. Y. F., Sarian, M. N., Wahab, R. A., Taher, M., Abdullahi, M. I. & Khatib, A., 2018, Phytoconstituents from Vernonia glaberrima Welw. Ex O. Hoffm. leaves and their cytotoxic activities on a panel of human cancer cell lines, pp. 22 in South African Journal of Botany 116 (10) on page 22, DOI: 10.1016/j.sajb.2018.02.391, http://zenodo.org/record/14036658
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- Is part of
- Journal article: 10.1016/j.sajb.2018.02.391 (DOI)
- Journal article: urn:lsid:plazi.org:pub:FF9FFF9BFF9F8963FA68FFEB3436FF98 (LSID)
- Journal article: http://zenodo.org/record/14036658 (URL)
- Journal article: http://publication.plazi.org/id/FF9FFF9BFF9F8963FA68FFEB3436FF98 (URL)