WOUND HEALING ACTIVITY OF GUETTARDA SPECIOSA LINN.

Traditionally the plant diversity was conserved through the temple premises based on their medicinal values. Medicinal activities of many temple plants are scientifically unexplored. The present research was focused to evaluate the wound healing activity of the sacred tree Guettarda speciosa commonly known as Indian lavender which is conserved in many temples and also promoted to grown as ornamental. The plant leaf is enriched with alkaloids, flavonoids, phenols, tannins, terpenoids, etc. Traditionally the leaf is used in cuts and wounds. Hence, the present research carried out to find the wound healing activity of ethanolic leaf extract of G. speciosa by excision wound model on Wistar albino female rats. 5% and 10% (w/w) leaf extract ointments were used for studying the wound healing activity. Lyramycin was used as a standard reference drug. The result showed that animals treated with 10% (w/w) leaf extract ointment possesses significant wound healing activity. The result confirmed and concluded that the activity of the extract is based on a dose-dependent manner.

Keywords: Wound healing, Guettarda speciosa, excision wound model, ointment, Lyramycin.