Published July 8, 2018
| Version v1
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SOLVENT FREE SYNTHESIS OF PYRROLO[2,1-A]ISOQUINOLINES UNDER MICROWAVE-IRRADIATION: AN ANTIOXIDANT POTENT.
Authors/Creators
- 1. Department of Chemistry, National Institute of Technology, M. G. Avenue, Durgapur, Burdwan West- 713209, West Bengal, India.
- 2. Department of Chemistry, Hooghly Institute of Technology (under DTET-GoWB), Hooghly-712103, West Bengal, India.
- 3. Department of Chemistry, Arambagh Government Polytechnic (under DTET-GoWB), Arambagh, Hooghly-712602, West Bengal, India.
Description
An environmentally benign protocol has been described for the synthesis of substituted pyrrolo[2,1-a]isoquinolines from 3-formyl chromone and 2-aryl/alkoxycarbonylmethylisoquinolium bromide using basic alumina as solid base in a solvent-free condition under microwave irradiation. All the synthesized compounds have also been screened for their antioxidant activities by DPPH method and were found to be significantly active with respect to Butylatedhydroxytoluene (BHT).
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