PPI prediction data (STRING 12.0 based)

An extensive dataset of binary physical protein-protein interaction extracted from STRING 12.0 (>12,000 organisms) with artificially generated negatives. The dataset includes 72M positive pairs with STRING confidence scores> 0.9 and 720M negative pairs. The corresponding protein sequences are located in the .fasta files. The generation of the negatives was derived from https://doi.org/10.1016/j.isci.2024.110371