Published August 30, 2024 | Version v1
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Single-cell datasets for Spherical Manifolds Capture Drug-Induced Changes in Tumor Cell Cycle Behavior

Description

Single-cell dataset for Spherical Manifolds Capture Drug-Induced Changes in Tumor Cell Cycle Behavior by Wen et al. This is a single-cell T47D ER+/HER2- cancer dataset, where rows are individual cells, and columns are proteomic features measured using iterative immunofluorescent imaging (4i). Cell cycle phase annotations are found in the 'phase' column, and the 'Metadata_well' column refers to nanomolar treatment doses of palbociclib, from an untreated population (0 nM), up to 1,000 nM. Data are z-normalized across all treatment conditions. Please refer to the manuscript for full experimental details.

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T47D.csv

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Additional details

Software

Repository URL
https://github.com/purvislab/SingleCell_HyperSphere
Development Status
Active