Published August 9, 2018 | Version v1

Screen of A6 and B7 TCR against a library of HLA-A*02:01 MHC-I peptides from the human exome

  • 1. Memorial Sloan Kettering Cancer Center

Description

T2 cells expressing a library of off targets (derived from A6 and B7 binding motifs in Hausmann 1999) are co-cultured with A6, B7. DMF5 or 1G4 expressing T cells (from a non-A2 donor) and minigenes from surviving cells are amplified.

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