The use of platelet – enriched plasma in the treatment of long - standing hard – to - heal wouds

Badyin I. Yu. The use of platelet – enriched plasma in the treatment of long - standing hard – to - heal wouds. ВІСНИК МОРСЬКОЇ МЕДИЦИНИ. 2018;2(79):60-66. ISSN 0049-6804.

DOI http://dx.doi.org/10.5281/zenodo.1307435

http://www.herald.com.ua

UDК 617-001.4-036.17-085.382:611.018.52

THE USE OF PLATELET – ENRICHED PLASMA IN THE TREATMENT OF LONG - STANDING HARD – TO - HEAL WOUNDS

I. Yu. Badyin

State Enterprise “Ukrainian Research Institute for Medicine of Transport”, Odessa

e-mail: ivanbadyin@gmail.com

Abstract

The number of patients with purulent-septic diseases of soft tissues is about 20-30% of all the patients of the surgical profile. Long – standing hard-to-heal (LSHH) wounds comprises the most part of this pathology. The causes of chronic LSHH wounds are their localization in areas with poor blood supply, antibiotic-resistant infection, trophic disorders of tissues in chronic venous, arterial insufficiency, home treatment accompanied by constant re-infection. Progressing prevalence of diabetes mellitus with diabetic angiopathy is a serious medical and social problem and leads to persistent disability and mortality. The possibility of using in the treatment process and managing of the biological potential of the patients’ own body on the basis of the use of platelet-enriched plasma (PEP) is a highly effective and minimally going for method of treatment. The objective: to study the modulation of the adaptive-reparative processes of the inflammatory response of LSHH wounds by growth factors of PEP. Materials and methods. Patients of the burns unit of the Kherson regional hospital. All the patients under observation received standard treatment depending on their indications. A group of patients was additionally subcutaneously injected into the lesion region by an autoplasma enriched with platelets. The use of PEP - therapy in the treatment of LSHH provides a wide range of local and systemic therapeutic effects, improves results, significantly reduces the terms of treatment and rehabilitation and improves the quality of life, which is economically important aspect.

Key words: hard-to-heal, platelet-enriched plasma, PEP – therapy.