Published July 9, 2024 | Version v1

Source data for the HDX-MS experiments in publication "Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase"

  • 1. Institute of Organic Chemistry and Biochemistry of the CAS
  • 2. University of Chemistry and Technology
  • 3. ROR icon Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

Description

Dataset of HDX-MS experiments related to the publication "Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase", published in Nature Communications with DOI: https://doi.org/10.1038/s41467-024-50933-6 

The differential HDX-MS experiments compare the apo and ligand-bound states of IMPDH from Mycobacterium smegmatis.

A description of the dataset is provided in the attached README file: IMPDH_HDX-MS_README.txt.

Detailed experimental conditions are available in the related publication.

Files

IMPDH_HDX-MS_repository.zip

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Additional details

Related works

Is supplement to
Journal article: 10.1038/s41467-024-50933-6 (DOI)