Published July 4, 2024 | Version v1

Source data for the kinetic assays in publication "Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase"

  • 1. Institute of Organic Chemistry and Biochemistry of the CAS
  • 2. ROR icon Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

Description

Datasets of enzyme kinetics related to the publication "Deciphering the allosteric regulation of mycobacterial inosine-5′-monophosphate dehydrogenase", published in Nature Communications with DOI: https://doi.org/10.1038/s41467-024-50933-6 

Individual files contain raw kinetic reaction data of the mycobacterial IMPDHs (wild type and mutant forms Mycobacterium smegmatis or wild type Mycobacterium tuberculosis) as a function of IMP, NAD+, GTP, ATP, ppGpp and Mg2+ concentration.

Individual data sets are presented as time data points of the absorbance at 340 nm in an Excel file with a linked Graphpad graphical link. Detailed experimental conditions are available in the related publication.

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SourceData.zip

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Related works

Is supplement to
Journal article: 10.1038/s41467-024-50933-6 (DOI)