Published June 28, 2024
| Version 1
Dataset
Open
Single-cell proteo-transcriptomic profiling reveals altered characteristics of stem and progenitor cells in patients receiving cytoreductive hydroxyurea in early-phase chronic myeloid leukemia
Authors/Creators
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1.
University of Gothenburg
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2.
Sahlgrenska University Hospital
Description
This repository contains CITE-seq data generated from CML stem and progenitor cells before and after hydroxyurea treatment using the BD Rhapsody Single-Cell Analysis System.
File descriptions:
1. RSEC-adjusted UMI count files generated using the BD Rhapsody Targeted Analysis Pipeline (v. 1.10.1):
- CartridgeS1_RSEC_MolsPerCell.csv
2. RSEC-adjusted UMI counts for cells remaining after cell quality filtering using SeqGeq software (genes expressed vs library size):
- CartridgeS1_RSEC_MolsPerCell_postQC.csv
3. Sample tag (sample of origin) calls for each putative cell, outputted by the BD Rhapsody Targeted Analysis Pipeline (v. 1.10.1).
- CartridgeS1_Sample_Tag_Calls.csv