Published May 2, 2019 | Version V1.0
Dataset Open

Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication: creating new models

Description

This data repository provides code and general instructions for creating new LINE-1 (L1) insertion site models as described in Flasch, et al., 2019:
https://www.sciencedirect.com/science/article/pii/S0092867419302338?via%3Dihub

Please see file L1_Simulation_Files_help.docx for more detailed information.

File L1Simulation_filelist.xlsx lists the files described in the Word file and found in L1Simulations.tar.gz.

Required large file ChrmsALL_table_sortEN.bed.gz is found individually. Importantly, like the paper analysis, this file is specific to the hg19 version of the human genome.

Please see the companion Zenodo data set
10.5281/zenodo.8233858
if you only want to access our insertion data and the resulting models we created.

 

Files

Files (32.9 GB)

Name Size
md5:3f6d62b4433e3ce07b996920b8dd7ed6
32.9 GB Download
md5:1dfc9ecfb2ab960719fa30649e7603a5
13.2 kB Download
md5:ab9602001bd30946069136bac68202e1
17.1 kB Download
md5:15d2ebbb8b5cdf80495c9f97f5bf5c9c
11.0 kB Download
md5:7cb82bef33a93c10ddcf2cede1a696f5
1.0 MB Download

Additional details

Related works

Is published in
Journal article: 10.1016/j.cell.2019.02.050 (DOI)