Generic residue numbering of the GAIN domain of adhesion GPCRs

The dataset corresponding to the publication:

• Generic residue numbering of the GAIN domain of adhesion GPCRs
  Florian Seufert, Guillermo Pérez-Hernández, Gáspár Pándy-Szekeres, Ramon Guixà-González, Tobias Langenhan, David E. Gloriam, Peter W. Hildebrand

  ReasearchSquare

  https://doi.org/10.21203/rs.3.rs-4761600/v1

The archive consists of three files:

• gaingrn_data.tgz

Contains the underlying data and object structures for the GAIN-GRN creation process and the python package availabe in https://github.com/FloSeu/GAIN-GRN. This can be downloaded manually and extracted in the respective GAIN-GRN/ directory or automatically retrieved via a dedicated function

• agpcr_gains.tgz

Contains the best (rank 1) PDB model of the ColabFold/AlphaFold2 workflow for each adhesion GPCR GAIN domain, named by its UniProt accession number.

• pkd_gains.tgz

Contains the best (rank 1) PDB model of the ColabFold/AlphaFold2 workflow for each polycystic kidney disease (PKD1) / PKD1-like 1 protein (PKD1L1) GAIN domain, named by its UniProt accession number.