Modification of zinc in the bone tissue of residents of the territories of the Dnipropetrovsk region with different ecology

Kalinicheva V. V. Modification of zinc in the bone tissue of residents of the territories of the Dnipropetrovsk region with different ecology. Актуальні проблеми транспортної медицини / Actual problems of transport medicine / 2018;1(51):136-140. ISSN 1818-9385

DOI http://dx.doi.org/10.5281/zenodo.1239532

http://aptm.org.ua

UDК 616.71-008.9: 547.1’147-048.77: 614.7 (477.63)      

MODIFICATION OF ZINC IN THE BONE TISSUE OF RESIDENTS OF THE TERRITORIES OF THE DNIPROPETROVSK REGION WITH DIFFERENT ECOLOGY

Kalinicheva V. V.

State Establishment "Dnipropetrovsk Medical Academy of Health Ministry of Ukraine"

Abstract

Influence of competitive relations of anthropogenic pollution of the environment and essential element on human bone tissue is actualized. The results of the study of zinc content in bone tissue of 42 inhabitants of ecologically contrasting territories by the ICP-AES / ICP-MS method are presented. Sample preparation of samples of bone tissue was conducted in accordance with the methodical requirements of MUK 4.1.1483-03. Intraoperatively, with an idiopathic coxarthrosis and aseptic necrosis of the femoral head, a 1-2 g bone tissue was taken. The subjects under radiologic signs did not have osteoporosis. It was found that in the bone tissue of the inhabitants of the industrial area, compared with the inhabitants of the control, zinc content was lower by 15.6 % (p = 0.016), and is 44.23 ± 2.9 mg/kg and 52.41 ± 1.44 mg/kg respectively. The fact that zinc is reduced in human bone tissue is established by us and corresponds to the identical results in the exposed animals, which proves the mechanism of development of bionatonic relations between zinc and lead. The risk of ecological determinism of reducing the zinc level in the bone tissue of the industrial region's inhabitants in terms of chances of 5.6 (95 % CI 3.15-9.8) times higher (p < 0.005), compared with residents of the control area.

Key words: zinc, bone tissue, trace elements, environment