Journal article Open Access

Virus entry: Molecular mechanism and biomedical applications

Dimitrov, Dimiter S.

Viruses have evolved to enter cells from all three domains of life--Bacteria, Archaea and Eukaryotes. Of more than 3,600 known viruses, hundreds can infect human cells and most of those are associated with disease. To gain access to the cell interior, animal viruses attach to host-cell receptors. Advances in our understanding of how viral entry proteins interact with their host-cell receptors and undergo conformational changes that lead to entry offer unprecedented opportunities for the development of novel therapeutics and vaccines.

Files (1.0 MB)
Name Size
article.pdf
md5:64b6bc7ceb49eaf25be02ff792d75e7e
1.0 MB Download
128
112
views
downloads
Views 128
Downloads 112
Data volume 116.8 MB
Unique views 124
Unique downloads 106

Share

Cite as