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Published October 19, 2014 | Version Acromegaly-v0.4.1

CushingAcromegalyStudy: PLOS One Revised Version

Authors/Creators

  • 1. UT Health Science Center
  • 2. University of Tennessee Health Sciences Center

Description

This version was the revised version based on the reviews from PLOS One. The reviewer comments are grouped into issues #39 #40 #41 #42 #43 #44 #45

The major change in this release is the switch to an age-adjusted model for transcript abundance. We grouped subjects into two groups, under 60 or 60 and above and then corrected based on that grouping. This affected several q-values. We also observed that older subjects had lower IGF-1 levels and lower magnitude transcriptional changes. This was addressed in issue #40

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CushingAcromegalyStudy-Acromegaly-v0.4.1.zip

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