A SHORT REVIEWON DRUG RESISTANCE AND COMPLICATIONSIN THERAPYOF TUBERCULOSIS

Chemotherapy is the most potent therapy for treatment of tuberculosis. In the chemotherapy of tuberculosis, resistance associated with treatment failures emerged and has become a common occurrence all around world. The multi-drug therapy is used to prevent the emergence of drug resistance mutants during the long duration of treatment. Resistance can be defined as single-drug, multi-drugs, depending on the number of drugs and/or which drugs are involved. The drug resistance tuberculosis more prevalent, lack the resources to implement adequate measures to control even the susceptible types of the disease. A high prevalence of primary multidrug-resistant tuberculosis, previous treatment for TB predisposes to the selection of multi drug resistance organisms and non-compliance is a major factor in allowing the resistant organisms to survive.