Published March 7, 2018 | Version v1

Full eQTL and caQTL summary statistics from the linear model

Authors/Creators

  • 1. Wellcome Trust Sanger Institute

Description

The summary statistic files contains the following columns:

  • phenotype_id
  • chr
  • pos
  • snp_id
  • distance
  • p_nominal
  • beta

The *.permuteted.txt.gz files are from the permutation pass of FastQTL and contains the following columns:

  • phneotype_id - ID of the tested molecular phenotype (in this particular case, the gene ID)
  • n_snps - Number of variants tested in cis for this phenotype
  • beta1 - MLE of the shape1 parameter of the Beta distribution
  • beta2 - MLE of the shape2 parameter of the Beta distribution
  • dummy - Dummy [To be described later]
  • snp_id - ID of the best variant found for this molecular phenotypes (i.e. with the smallest p-value)
  • distance - Distance between the molecular phenotype - variant pair
  • p_nominal - The nominal p-value of association that quantifies how significant from 0, the regression coefficient is
  • beta - The slope associated with the nominal p-value of association [only in version > v2-184]
  • p_perm - A first permutation p-value directly obtained from the permutations with the direct method. This is basically a corrected version of the nominal p-value that accounts for the fact that multiple variants are tested per molecular phenotype.
  • p_beta - A second permutation p-value obtained via beta approximation. We advice to use this one in any downstream analysis.

Files

Files (35.1 GB)

Name Size
md5:f19ff329037950ebda82d73de92976da
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