Journal article Open Access

Haloxylon Scoparium: An Ethnopharmacological Survey, Phytochemical Screening and Antibacterial Activity against Human Pathogens Causing Nosocomial Infection

N. Fatehi; M. Allaoui; H. Berbaoui; A. Cheriti; N. Boulenouar; N. Belboukhari

Nosocomial infections occur worldwide, both in the developed and developing world. They are a major
cause of death and increased morbidity in hospitalized patients. This study deals with the valorization of medicinal
plants of southwest Algeria, in order to find new bioactive natural productsagainst human pathogens causing
nosocomial infection.
Haloxylon Scoparium (Chenopodiaceae family) is a local medicinal plant, which has been used extensively in the
southwestern part of Algeria. It was subjected to an ethnopharmacological survey,phytochemical screening and antinosocomial
activity. The ethnopharmacological survey revealed that the H. Scopariumis used to treat numerous human
diseasesespecially the infectious one such as skin infections, urinaryandgenitalinfections.Therefore, the H. scoparium
aerial part was subjected to a phytochemical screening. Then its crude extracts, including, acetone, ethanol, methanol,
chloroform, dichloromethane, chlorohydric and water extracts were tested against three pathogens causing nosocomial
infectionusing the disc diffusion method. As a result, all the phytochemical constituents were found to be present in the
aerial part of H. scoparium. The methanolic extract was found more bioactive comparing to the other extracts.

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