CYTOTOXIC EFFECT OF LOW MOLECULAR WEIGHT PROTEIN ISOLATED FROM CROTALARIA PALLIDA

Low molecular weight proteins (LMWPs) were isolated from Crotalaria pallida using Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE). The antimitotic assay has been investigated using onion root tips whereas apoptosis assay was conducted on MCF-7 cell lines. A 14 kDa protein has been identified as potent antitumor agent. Key words: Low Molecular weight proteins, SDS-PAGE, apoptosis, antitumor agent, Crotalaria pallida