Published April 30, 2024 | Version v1

Genes regulated by CARTp/GPR160 in the dorsal horn of the spinal cord

  • 1. Department of Pharmacology and Physiology, and Institute for Translational Neuroscience, Saint Louis University School of Medicine, St. Louis, MO

Description

Analysis of the dorsal horn spinal cord (DH-SC) after an intrathecal injection of CARTp or CARTp with a neutralizing GPR160 antibody after 1hr. Results provide insight into genes regulated by CARTp/GPR160-induced behavioral hypersensitivities in the DH-SC.

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Funding

National Institutes of Health
Discovery and validation of a novel orphan GPCR as a target for therapeutic intervention in neuropathic pain 1R01NS113257-01