Published April 28, 2024 | Version v1

Data for paper: Transfer learning for cross-context prediction of protein expression from 5'UTR sequence

  • 1. University of Bristol

Description

This depsit contains data for the paper entitled: "Transfer learning for cross-context prediction of protein expression from 5'UTR sequence".

The rebeca.zip file contains a snapshot of the rebeca package which can be used to train, fine tune and test the CONV-LSTM model used in this study.

The datasets.zip file contains the compiled sequence to expression datasets from across all Flow-seq expressions considered in this study. 

The analysis.zip file contains all data files and jupyter notebooks necessary to reproduce our analysis. Each Flow-seq study has a dedicated folder (e.g., `fepB') with two sub-folders: 1. The `data\_split' folder, which contains the steps necessary to split the Flow-seq data for our ML experiments (a `readme.txt' file describes the input and output files and a jupyter notebook is available to reproduce the data split); 2. The `data\_analysis' folder, which contains a jupyter notebook and the necessary input files to reproduce the analysis of our experiments.

Files

analysis.zip

Files (19.6 GB)

Name Size
md5:00d7bd7d08f5c8d388c1ce1e69fc4bcf
7.0 GB Preview Download
md5:f33bca7d29f9b5c3f95e7ecd8d9a40ac
75.5 MB Preview Download
md5:136db226bd954ed88a5c6851b09fc418
12.5 GB Preview Download

Additional details

Funding

Engineering and Physical Sciences Research Council
EPSRC/BBSRC Centre for Doctoral Training in Synthetic Biology EP/L016494/1
Biotechnology and Biological Sciences Research Council
BrisEngBio BB/W013959/1
Engineering and Physical Sciences Research Council
Turing Institute EP/N510129/1
Royal Society
Adaptive Genetic Circuits URF\R\221008

Software

Repository URL
https://gitlab.com/Pierre-Aurelien/rebeca
Programming language
Python