Published May 15, 2024 | Version v1
Dataset Open

Conformational changes in insulin receptor illuminated by live-cell linear dichroism imaging and a FLIP biosensor

Authors/Creators

  • 1. ROR icon Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
  • 2. ROR icon Charles University

Description

Response of GP2(1)-eGFP-CD59, a FLIP biosensor co transfected with insulin receptor against anatgonists and agonists of IR was measured and qunatified using polarization-resolved fluorescence microscopy. Linear dichoirism values were measured by analyinzing cells using already published imageJ macros (Bondar, Rybakova et al. 2021). This data set contains both raw images obtained from polarization micrscopy and analyzed data.

Files

Analayzed GP2(1)-eGFP-CD59+ IR-OFP.zip

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