Published April 2, 2024
| Version V1
Dataset
Open
Reward perseveration is shaped by GABAA-mediated dopamine pauses: Histology from Behavior Data Mice
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1.
Duke University
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2.
Duke University School of Medicine
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3.
Aligning Science Across Parkinson's
Description
Histology images for the experimental +HTP behavior mice in the dataset 10.5281/zenodo.10903566. This histology was used to generate the following figures in the paper "Reward perseveration is shaped by GABAA-mediated dopamine pauses":
- Ext. Fig 3, panel d
Specifics of the data:
- HTP_Histo_Cohort_VX.zip contains the raw images (Olympus .vsi files) and drawn ROIs and fluorescence analysis (MATLAB files) for each mouse/tissue section in cohort VX
- HTP_Histo_Cohort_VZ.zip contains the raw images (Olympus .vsi files) and drawn ROIs and fluorescence analysis (MATLAB files) for each mouse/tissue section in cohort VZ
- HTP_Histo_Cohort_VAJ.zip contains the raw images (Olympus .vsi files) and drawn ROIs and fluorescence analysis (MATLAB files) for each mouse/tissue section in cohort VAJ
- HTP_Histo_Cohort_VAK.zip contains the raw images (Olympus .vsi files) and drawn ROIs and fluorescence analysis (MATLAB files) for each mouse/tissue section in cohort VAK
- Behavior_summary_data_HTP_Histology.csv contains the summarized fluorescence quantification per animal
Files
Behavior_summary_data_HTP histology.csv
Files
(38.3 GB)
| Name | Size | |
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md5:f079ed0c6bce1f9054b7c9a18156dacd
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1.5 kB | Preview Download |
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md5:6a9859f39c6bed3dad0e7c6117a252d5
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3.3 GB | Preview Download |
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md5:1a76922d795f14416a4e7b4537f3f41f
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12.7 GB | Preview Download |
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md5:60197725bf296bcf825194a6a0e3b0fc
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11.3 GB | Preview Download |
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md5:9ec8d381bbc591d6d033205bb1e453ab
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10.9 GB | Preview Download |
Additional details
Funding
- Aligning Science Across Parkinson's
- Circuit Mechanisms for Dopamine Neuron Vulnerability and Resilience in PD ASAP-020607
Software
- Repository URL
- https://github.com/tadrosslab/VTA_GABA_paper
- Programming language
- MATLAB