Published April 2, 2024 | Version V1

Reward perseveration is shaped by GABAA-mediated dopamine pauses: Fiber Photometry Data

  • 1. ROR icon Duke University
  • 2. ROR icon Duke University School of Medicine
  • 3. ROR icon Aligning Science Across Parkinson's

Description

Fiber photometry data. These data were used to generate the following figures in the paper "Reward perseveration is shaped by GABAA-mediated dopamine pauses":

  • Figure 3, all panels
  • Ext. Fig 4, all panels

Specifics of the data:

  • FiberPho_Cohort_*.zip files contain all of the raw fiber photometry and behavior data for each mouse, grouped by cohort.
  • FiberPho_Histo_Cohort_*.zip files contain the histological images and ROIs for each mouse, grouped by cohort. 
  • HTP_grouped_data.zip contains the grouped analysis fiber photometry and behavior MATLAB files for the experimental group.
  • ddHTP_grouped_data.zip contains the grouped analysis fiber photometry and behavior MATLAB files for the control group.
  • The various .csv files contain the summarized mouse, cohort, and analysis details and data.

 

Files

ddHTP controls_grouped_data.zip

Files (111.1 GB)

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Additional details

Funding

Aligning Science Across Parkinson's
Circuit Mechanisms for Dopamine Neuron Vulnerability and Resilience in PD ASAP-020607

Software

Repository URL
https://github.com/tadrosslab/VTA_GABA_paper
Programming language
MATLAB