Published May 23, 2024 | Version v3
Software Open

Towards drift-free high-throughput nanoscopy through adaptive intersection maximization

  • 1. ROR icon University of Illinois Urbana-Champaign

Contributors

Researcher:

  • 1. ROR icon University of Illinois Urbana-Champaign

Description

This is the code repository for Adaptive Intersection Maximization (AIM)-based high-speed drift correction algorithm for single molecule localization microscopy. The details are presented in our paper entitled "Towards drift-free high-throughput nanoscopy through adaptive intersection maximization".

The code repository includes example code to run AIM on the sample simulated and experimental datasets. We provided four experimental datasets (Origami_PAINT, Microtublue_3d, Tissue_colon and CTCF_MCF10A_DRB_6h) and one simulated dataset (simulationSMLM) in MATLAB mat format available at Dryad. Please download these dataset and put them in the Data folder.

Details can be found in "README.md" and "User Guide for AIM.pdf". 

Files

AIM_Code.zip

Files (20.3 MB)

Name Size Download all
md5:1a8489b977fd0aebb3dc4e77aac5af82
20.3 MB Preview Download

Additional details

Related works

Is supplement to
Dataset: 10.5061/dryad.2v6wwpzw3 (DOI)

Funding

National Institutes of Health
Imaging nanoscale chromatin folding in early carcinogenesis 5R01CA254112-03
National Institutes of Health
Three dimensional nanoscale nuclear architecture mapping based taxonomy of precursor lesions for predicting colorectal cancer risk 5R01CA232593-04
National Institutes of Health
Super-Resolution Imaging of Higher-Order Heterochromatin Structure for Early Detection of Lung Carcinogenesis 1R21CA259787-01A1

Dates

Updated
2024-04-17

Software

Repository URL
https://github.com/YangLiuLab/AIM
Programming language
MATLAB , C