Published July 2, 2024 | Version v2

Generative AI in the Advancement of Viral Therapeutics for Predicting and Targeting Immune-Evasive SARS-CoV-2 Mutations

  • 1. ROR icon Jeonbuk National University

Description

This dataset encompasses and describes the following features:

  • Mutations in viruses like SARS-CoV-2 can make them escape vaccines and treatments.
  • Accurately predicting these mutations is crucial for developing effective countermeasures.
  • The study uses a type of AI called a Generative Adversarial Network (GAN) to analyze the virus's spike protein, which plays a key role in infection.
  • The GAN generates protein sequences similar to natural ones, but which are also likely to evade immune responses.
  • By analyzing these generated sequences, the researchers improve their AI model's ability to predict real-world escape mutations.
  • This improved prediction could help design better vaccines and treatments, and prepare for future viral threats.

Files

dataset.zip

Files (768.1 MB)

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Additional details

Related works

Is supplement to
Dataset: 10.5281/zenodo.7142638 (DOI)

Software

Repository URL
https://github.com/PremSinghBist/SarsGAN
Programming language
Python
Development Status
Active