Published January 29, 2024
| Version v1
Dataset
Open
Datasets: Natural killer cells associate with malignant epithelial cells in the pancreatic ductal adenocarcinoma tumor microenvironment
Contributors
Data collector (2):
Other:
Project manager:
Project member (2):
Researcher (5):
et al. Show all 12 contributors
Contributors
Contact person:
Data collector (2):
Other:
Project manager:
Project member (2):
-
1.
Georgetown University Medical Center
-
2.
Sidney Kimmel Comprehensive Cancer Center
-
3.
Johns Hopkins University
Description
The following are necessary data files for the manuscript "Natural killer cells associate with malignant epithelial cells in the pancreatic ductal adenocarcinoma tumor microenvironment":
- .zip files for TMA_1, TMA_2, TMA_3, and TMA_4 are .mcd files acquired from imaging mass cytometry (IMC) for each slide of the pancreas TMA slide series
- pancreas_TMA_sample_info.xlxs includes info on all samples of the TMA slide series that were imaged by IMC
- custom_gates_0.zip includes histoCAT-derived single cell data files from all IMC samples in the pancreas TMA to be used for single cell analyses in R
- PDAC_IMC.RDS is a Seurat object of the IMC-derived PDAC single cell data to use for single cell and spatial analyses
- PDAC_sce is a SingleCellExperiment object of IMC-derived PDAC single cell data to use for spatial analyses
- mat.RDS is a distance matrix of PDAC cell types to use in R to generate network graph (Figure 2)
Files
custom_gates_0.zip
Files
(32.3 GB)
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md5:98d27fbab88e382d2a4507995923556a
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md5:c5e8183e0b3073f894c7b2858f1da4b5
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md5:832ec92afe41c34039a622480566e5fc
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md5:d41d8cd98f00b204e9800998ecf8427e
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0 Bytes | Download |
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md5:c68854a6586a5de291cf1456be046d13
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md5:6e07700cc06e7705b55e16b0fb0d464c
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5.8 GB | Preview Download |
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md5:3767b143b40ef9fc02e285cbd915eb16
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md5:28cd709bab3d4c837a4a8dbcfa7a8593
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md5:3b798455327c3c624303063a917bc52b
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9.5 GB | Preview Download |
Additional details
Funding
- National Institutes of Health
- Training Grant in Tumor Biology 5T32CA009686-10
- National Institutes of Health
- Pancreatic Stellate Cell (PSC) Engagement of Natural Killer (NK) cells in the Pancreatic Ductal Adenocarcinoma (PDAC) Tumor Microenvironment F31CA261125
- Achievement Rewards for College Scientists Foundation
- NA Matt Riddle Scholar
Dates
- Available
-
2024-05-23
Software
- Repository URL
- https://github.com/Weiner-Lab/NaturalKillerCells_PDAC
- Programming language
- R
- Development Status
- Active