Published 2024
| Version V2
Dataset
Open
QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration
Authors/Creators
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Advani, Jayshree
(Researcher)1
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Mehta, Puja A.
(Researcher)2, 3, 4
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Hamel, Andrew R.
(Researcher)2, 3, 4
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Mehrotra, Sudeep
(Researcher)2, 3, 4
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Kiel, Christina
(Researcher)5
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Strunz, Tobias
(Researcher)5
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Diaz, Ximena Corso
(Researcher)1
- Kwicklis, Madeline (Researcher)1
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Asten, Freekje van
(Researcher)1
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Ratnapriya, Rinki
(Researcher)1
- et al. Show all 17 authors
Authors/Creators
-
Advani, Jayshree
(Researcher)1
-
Mehta, Puja A.
(Researcher)2, 3, 4
-
Hamel, Andrew R.
(Researcher)2, 3, 4
-
Mehrotra, Sudeep
(Researcher)2, 3, 4
-
Kiel, Christina
(Researcher)5
-
Strunz, Tobias
(Researcher)5
-
Diaz, Ximena Corso
(Researcher)1
- Kwicklis, Madeline (Researcher)1
-
Asten, Freekje van
(Researcher)1
-
Ratnapriya, Rinki
(Researcher)1
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Chew, Emily Y.
(Researcher)6
- Hernandez, Dena G. (Researcher)7
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Montezuma, Sandra R.
(Researcher)8
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Ferrington, Deborah A.
(Researcher)8
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Weber, Bernhard H. F.
(Researcher)5, 9
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Segrè, Ayellet V.
(Supervisor)2, 3, 4
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Swaroop, Anand
(Supervisor)1
- 1. Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA
- 2. Ocular Genomics Institute, Department of Ophthalmology, Massachusetts Eye and Ear, Boston, Massachusetts, USA
- 3. Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA
- 4. The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
- 5. Institute of Human Genetics, University of Regensburg, Regensburg, Germany
- 6. Division of Epidemiology and Clinical Applications, Clinical Trials Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, USA
- 7. Laboratory of Neurogenetics, National Institute of Aging, National Institutes of Health, Bethesda, Maryland, USA
- 8. Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, Minnesota, USA
- 9. Institute of Clinical Human Genetics, University Hospital Regensburg, Regensburg, Germany
Description
The summary statistics (nominal p-values, beta and standard error) for all significant variant-CpG pair mQTLs, all significant variant-gene pair eQTLs, and all significant CpG-gene pair eQTMs identified in retina in the Advani et al., https://www.researchsquare.com/article/rs-3011096/v1.
README: The chr positions are in genome build 38, and the chr positions in the variant IDs, e.g., 'rs201942322:649192:A:T' are in build hg19 (b37).