Published November 28, 2023 | Version v1
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ChemProp2 Dataset: Investigating potential biotransformations with a panel of 23 Drugs on Synthetic Community (Com20) to elucidate Drug-Microbiome-Host Dynamics

Authors/Creators

  • 1. ROR icon University of Tübingen
  • 2. University of Tuebingen, Interfaculty Institute of Micrbiology and Infection Medicine, Tübingen 72076, Germany

Description

Tested 23 drugs against Synthetic community (Com20) at two different timepoints (t=0, t= 2 hrs) to look for potential biotransformations

List of drugs tested:
Acarbose, Clemizole, Amlodipine, Clindamycin, Amoxicillin, Clomifen, Aprepitant, Clotrimazole, Avermectin B1, Diacerein, Azithromycin, Dicumarol, Control, Dienestrol, Benzbromarone, Dienogest, Ceterizin, Doxycycline hyclate, Chlorpromazine, Duloxetin, Chlorprothixene, Erythromycin, Cilnidipine, Ethinylestradiol

Samples were measured (in March 18/19, 2023) using an UHPLC-Q Exactive HF Orbitrap mass spectrometer, equipped with a C18 column, following the LC-MS/MS method.

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