Data from : Metabolic footprint of Vero E6 cells highlights the key metabolic routes associated with SARS-CoV-2 infection and response to drug combinations

This dataset contains representative 1D 1H NMR spectra and data used in the manuscript " Metabolic footprint of Vero E6 cells highlights the key metabolic routes associated with SARS-CoV-2 infection and response to drug combinations " . 

The present study used Nuclear Magnetic Resonance-based metabolic footprinting to characterize the secreted cellular metabolite levels (exometabolomes) of Vero E6 cells in response to SARS-CoV-2 infection and to two candidate drugs (Remdesivir, RDV and Azithromycin, AZI). 

Supplementary File 1.zip = Representative 1D 1H NMR profiles of examined VE6 esometabolomes, 

Supplementary File 2.xlsx = Average Mean ± Standard Deviations of NMR relative quantified data (integrals, a.u.) from examined VE6 esometabolomes. 

Supplementary File 3.csv  = p–values and associated False Discover Rate (FDR) derived from univariate ANOVA with Fischer's LDS post-hoc test  comparisons carried out on  NMR relative quantified data.

List of Supplementary Files derived from Metabolite Set Enrichment Analysis (MSEA) : 

Supplementary File 4.csv = Tabular Results from MSEA performed on VE6+ VE6- comparison.

Supplementary File 5.csv = Tabular Results from MSEA performed on VE6+ RDV vs.  VE6+ comparison.

Supplementary File 6.csv = Tabular Results from MSEA performed on VE6+ AZI vs.  VE6+ comparison.

Supplementary File 7.csv = Tabular Results from MSEA performed on VE6+ R+A vs.  VE6+ comparison.