Published April 25, 2024 | Version v2.0.0

Prymnesium parvum 12B1 polyketide synthase (PKS) domain and module analysis

Authors/Creators

  • 1. ROR icon University of California San Diego
  • 2. ROR icon Scripps Institution of Oceanography

Description

The .zip file contains source data and code for an analysis that determines the modular structure from the domain structure of type I modular polyketide synthases (PKSs) in the Prymnesium parvum strain 12B1 gene annotation. In brief, a regex is used against a string representation of the PKS domain structures to determine the module structure. Some manual modifications for calling modules were performed where they deviated. Resulting data is available in the .zip file as .bed, .FASTA, .xlsx files. See Manuscript for further details.

For versions after v1.0.5, analyses of B-type PKZILLA-B1 (i.e. from strain RCC3426) are also included. 

Files

PKS domain to module conversion script.zip

Files (8.3 MB)

Name Size
md5:7bfe4b6307dc443d29d4415cf9f4ec96
8.3 MB Preview Download

Additional details

Related works

Continues
Dataset: 10.5281/zenodo.10023460 (DOI)
Dataset: 10.5281/zenodo.10011739 (DOI)
Dataset: 10.5281/zenodo.11094341 (DOI)

Funding

National Institutes of Health
ELUCIDATING THE BIOSYNTHESIS OF A MODEL LADDER-FRAME POLYETHER TOXIN F32ES032276