Published October 17, 2023 | Version v1

Illumina Infinium MethylationEPIC data for theca cells from normal cycling and polycystic ovary syndrome affected females

  • 1. ROR icon Baylor College of Medicine
  • 2. ROR icon Virginia Commonwealth University
  • 3. Penn State Hershey
  • 4. ROR icon University of Pennsylvania

Description

Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder that affects reproductive-age women. Epigenetic alterations have been implicated in the development and progression of PCOS. DNA methylation is one such epigenetic modification that plays a crucial role in regulating gene expression. To investigate the epigenetic differences in theca cells between normally cycling and PCOS-affected women, as well as the impact of azacytidine and forskolin treatments, we conducted experiments using the Infinium MethylationEPIC assay.

Illumina.Infinium.MethylationEPIC.idats.zip - IDAT files generated from the Infinium MethylationEPIC assay data

no_azacytidine_forskolin.zip, no_azacytidine_control.zip, azacytidine_control.zip, azacytidine_forskolin.zip - comparisons results from RNBeads (https://rnbeads.org/)

 

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