Bioactive Metabolites and Antiquorum Activity of Nyctanthes Arbor-Tristis Extracts

Traditional medicine has played a main role in India. Anti Quorum sensing activity was detected on Nyctanthes arbor-Tristis [leaf,flower and stem]extracts and confirmed on by using Pyocyanin quantification assay, Staphylolytic  broth activity and Biofilm inhibition assays.  The moderate amount of proteins were detected in SDS-PAGE analysis and was observed using silver staining. The  FTIR, HPLC analysis showed the presence of compounds like alkaloids, phenols. terpenoids, saponins. flavonoids and glycosides. It also includes Benzoic acid, octadecane, cyclopentane, oleic acid, Tetra decane, pentacosane etc.The GC-MS analysis revealed the presence of 63 natural compounds from the Nyctanthes arbor-Tristis [leaf,stem,and flower] extracts. Some of the active compounds include Heneicosane, dodecanoic acid, eicosane Oleic Acid, tetracontane, Cyclopenta, tetradecanoic acid, eicosane, dodecanoic acid etc. The bioactive constituents found in the ethanol extracts of Nyctanthes arbor-Tristis [leaf, stem, and flower] could act as the lead compounds, or pharmacological agents. These bioactive metabolites  have the possibility to act as molecular targets in the drug development. The prime initiative should focus on the cultivation and conservation of medicinal plants with pharmacological importance.