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Published March 22, 2026 | Version 1.0.0
Dataset Open

Precomputed diffusion kernels for the process2phenotype R package

Authors/Creators

  • 1. ROR icon University of Cambridge

Description

Precomputed regularised Laplacian diffusion kernels for protein-protein interaction networks, for use with the process2phenotype R package (https://github.com/adjajadikerta/process2phenotype).

Files:
- BioGRID_Human_RLK.rds — Regularised Laplacian kernel for the human BioGRID interactome (24,961 × 24,961 matrix)
- BioGRID_Yeast_RLK.rds — Regularised Laplacian kernel for the yeast BioGRID interactome (7,345 × 7,345 matrix)

Kernels were computed in 2020 using diffuStats::regularisedLaplacianKernel() on binary protein-protein interaction data from BioGRID (Oughtred et al., 2019).

Files

Files (4.2 GB)

Name Size
md5:f1a390b45e53fa5ed5e95316e722acfb
3.8 GB Download
md5:8b06987a9ee73d31223b04da83dfa4f3
363.8 MB Download

Additional details

Related works

Is supplemented by
Software: https://github.com/adjajadikerta/process2phenotype (URL)

Dates

Created
2020-06-01
Date kernels were computed
Available
2026-03-22
Date posted

Software

Repository URL
https://github.com/adjajadikerta/process2phenotype
Programming language
R
Development Status
Active

References

  • Oughtred, R. et al. The BioGRID interaction database: 2019 update. Nucleic Acids Res 47, D529–D541 (2019).
  • Picart-Armada, S. et al. diffuStats: an R package to compute diffusion-based scores on biological networks. Bioinformatics 34, 533–534 (2018).